Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 9/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822937 | 1.00 | LMNA (0.53) | LMNAADKP2RY6P2RY14NT5E | |
| SCHEMBL8197007 | 0.91 | LMNA (0.56) | LMNAADKP2RY6P2RY14NT5E | |
| SCHEMBL8197013 | 0.91 | LMNA (0.56) | LMNAADKP2RY6P2RY14NT5E | |
| SCHEMBL7204443 | 0.91 | LMNA (0.49) | LMNAADKP2RY6P2RY14NT5E | |
| SCHEMBL8193244 | 0.91 | LMNA (0.49) | LMNAADKP2RY6P2RY14NT5E | |
| SCHEMBL8203611 | 0.87 | LMNA (0.60) | LMNAADKP2RY6 | |
| SCHEMBL8203607 | 0.87 | LMNA (0.60) | LMNAADKP2RY6 | |
| SCHEMBL9222549 | 0.86 | LMNA (0.70) | LMNAADKP2RY6P2RY14NT5E | |
| SCHEMBL9218284 | 0.86 | LMNA (0.70) | LMNAADKP2RY6P2RY14NT5E | |
| SCHEMBL3817143 | 0.86 | LMNA (0.39) | LMNAADKP2RY6NAAAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114520-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-09-05 | — | — | US | disclosed |