Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202582 | 0.90 | CRHR1 (0.48) | CRHR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL21886231 | 0.83 | CRHR1 (0.62) | CRHR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL21886137 | 0.83 | CRHR1 (0.52) | CRHR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8202018 | 0.81 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7535444 | 0.80 | CRHR1 (0.58) | CRHR1LMNATP53 | |
| SCHEMBL7534738 | 0.79 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL20733327 | 0.79 | CRHR1 (0.75) | CRHR1MEN1KMT2A | |
| SCHEMBL7483912 | 0.78 | CRHR1 (0.51) | CRHR1LMNA | |
| SCHEMBL7475973 | 0.77 | CRHR1 (0.46) | CRHR1LMNA | |
| SCHEMBL21886413 | 0.77 | CRHR1 (0.58) | CRHR1LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |