SCHEMBL8204151

SCHEMBL8204151

CC(=O)OCCCNCCN(CCCOC(C)=O)CCNCCN(CCCOC(C)=O)CCCOC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
PAOX Q6QHF9 3/20 0.40
CHRM2 P08172 3/20 0.35
LMNA P02545 3/20 0.35
HTR1A P08908 2/20 0.35
GAA P10253 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
DRD3 P35462 1/20 0.35
SCN1A P35498 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KCNH2 Q12809 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
CHRM1 P11229 3/20 0.34
CHRM3 P20309 3/20 0.34
CHRM5 P08912 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CHRM4 P08173 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7861476 0.98 ALDH1A1 (0.42) ALDH1A1PAOXCHRM2LMNAHTR1A
SCHEMBL67905 0.84 ALDH1A1 (0.58) ALDH1A1PAOXCHRM2LMNAHTR1A
SCHEMBL68495 0.78 ALDH1A1 (0.56) ALDH1A1PAOXCHRM2LMNAHTR1A
SCHEMBL23787609 0.77 ALDH1A1 (0.61) ALDH1A1PAOXCHRM2LMNAHTR1A
SCHEMBL30604754 0.76 ALDH1A1 (0.65) ALDH1A1PAOXTSHRFAAH
SCHEMBL65382 0.75 MEN1 (0.46) ALDH1A1CHRM2LMNAHTR1AGAA
SCHEMBL611933 0.75 ALDH1A1 (0.58) ALDH1A1PAOXCHRM2LMNAHTR1A
SCHEMBL13003549 0.75 ALDH1A1 (0.58) ALDH1A1CHRM2LMNAHTR1AGAA
SCHEMBL7796998 0.74 ALDH1A1 (0.50) ALDH1A1CHRM2LMNAHTR1AGAA
SCHEMBL5551561 0.74 PAOX (0.52) ALDH1A1PAOXLMNACYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6028193-A CATALYZING THE OXIDATION REACTION IN PRESENCE OF A TRANSITION METAL COMPLEX WHICH CONTAINS A CYCLIC POLYFUNCTIONAL AMINE COMPOUND HAVING AT LEAST THREE NITROGEN ATOMS IN THE RING FORMING MOLECULAR MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed