Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 5/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521566 | 0.95 | HINT1 (0.59) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5367078 | 0.93 | HINT1 (0.67) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL8446274 | 0.88 | HINT1 (0.58) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5346021 | 0.88 | HINT1 (0.68) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5356827 | 0.84 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5355030 | 0.84 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5347800 | 0.84 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5347821 | 0.84 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5352845 | 0.83 | HINT1 (0.67) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL8204402 | 0.82 | HINT1 (0.48) | HINT1GSK3ARPS6KA3MAPK14PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054441-A | Antiinflammatory agents; treatment of bacterial, viral or fungal infections; autoimmune diseases | PRO-NEURON, INC. (US) | 2000-04-25 | — | — | US | disclosed |