Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201735 | 0.80 | HRH1 (0.50) | CYP19A1EPHX2SLC6A3LMNACNR1 | |
| SCHEMBL7382843 | 0.76 | CYP19A1 (0.44) | CYP19A1MEN1KMT2ASLC6A3MITF | |
| SCHEMBL318816 | 0.72 | CYP19A1 (0.47) | CYP19A1MEN1KMT2ASLC6A3MITF | |
| SCHEMBL3637472 | 0.71 | CYP19A1 (0.44) | CYP19A1EPHX2MITFLMNACNR1 | |
| SCHEMBL7714102 | 0.71 | CYP19A1 (0.44) | CYP19A1EPHX2MEN1KMT2AMITF | |
| SCHEMBL757076 | 0.71 | CYP19A1 (0.44) | CYP19A1EPHX2MEN1KMT2AMITF | |
| SCHEMBL3688208 | 0.71 | CYP19A1 (0.44) | CYP19A1EPHX2MEN1KMT2AMITF | |
| SCHEMBL4618800 | 0.71 | HRH1 (0.62) | CYP19A1KMT2AMITFLMNACNR1 | |
| SCHEMBL7331536 | 0.71 | CYP19A1 (0.46) | CYP19A1MEN1KMT2ASLC6A3 | |
| SCHEMBL11796722 | 0.70 | IDO1 (0.41) | CYP19A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022987-A | Aryl substituted alkylsilanes and a preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2000-02-08 | — | — | US | disclosed |