Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 6/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599884 | 0.82 | TSHR (0.42) | HRH1HTR2AMTNR1AMTNR1BTAAR1 | |
| SCHEMBL5485540 | 0.80 | RIPK1 (0.52) | TAAR1 | |
| SCHEMBL8204422 | 0.80 | CYP19A1 (0.45) | EPHX2CNR1CNR2SLC6A3LMNA | |
| SCHEMBL3290730 | 0.76 | HRH1 (0.68) | HRH1HTR2AMTNR1AMTNR1BTAAR1 | |
| SCHEMBL1532968 | 0.76 | SLC6A4 (0.38) | HRH1HTR2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL8204424 | 0.75 | HTR2A (0.46) | HRH1HTR2ATAAR1CHRM2CHRM1 | |
| SCHEMBL2732016 | 0.73 | HRH1 (0.65) | HRH1HTR2AMTNR1AMTNR1BTAAR1 | |
| SCHEMBL844862 | 0.73 | HRH1 (0.65) | HRH1HTR2AMTNR1AMTNR1BTAAR1 | |
| SCHEMBL27321444 | 0.73 | HRH1 (0.65) | HRH1HTR2AMTNR1AMTNR1BTAAR1 | |
| SCHEMBL8204418 | 0.73 | IDO1 (0.40) | CNR1CNR2OPRM1CYP3A4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022987-A | Aryl substituted alkylsilanes and a preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2000-02-08 | — | — | US | claimed |
| US-6022987-A | Aryl substituted alkylsilanes and a preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2000-02-08 | — | — | US | disclosed |