Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 11/20 | 0.47 |
| ▸ | CNR2 | P34972 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371553 | 0.87 | CYP1A2 (0.51) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3371556 | 0.87 | CYP1A2 (0.51) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8199975 | 0.86 | SLC6A2 (0.46) | ACACBCNR1CNR2FFAR1SLC6A2 | |
| SCHEMBL8772670 | 0.84 | FDFT1 (0.56) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8623146 | 0.78 | KMT2A (0.46) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8199320 | 0.78 | KMT2A (0.46) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3475482 | 0.76 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL8191921 | 0.75 | CNR1 (0.48) | ACACBCNR1CNR2 | |
| SCHEMBL8772772 | 0.75 | APEX1 (0.43) | CNR1CNR2FDFT1 | |
| SCHEMBL8191925 | 0.75 | CNR1 (0.42) | ACACBCNR1CNR2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017956-A | AN ANTITUMOR AGENT, AN ENZYME INHIBITOR FOR INHIBITING PROTEIN-FARNESYL TRANSFERASE TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5919786-A | ANTITUMOR AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| US-5849747-A | N, n-disubstituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0805154-A1 | N,N-DISUBSTITUTED AMIC ACID DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |