Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | ACACB | O00763 | 4/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624864 | 0.88 | FDFT1 (0.43) | CNR1CNR2PTGESTPH1UTS2R | |
| SCHEMBL8619447 | 0.88 | UTS2R (0.43) | CNR1CNR2TPH1UTS2R | |
| SCHEMBL8125412 | 0.85 | PIN1 (0.39) | UTS2R | |
| SCHEMBL8623160 | 0.82 | UTS2R (0.42) | UTS2R | |
| SCHEMBL8623018 | 0.81 | FDFT1 (0.35) | CNR1CNR2TPH1UTS2R | |
| SCHEMBL8623571 | 0.80 | FDFT1 (0.40) | CNR1CNR2 | |
| SCHEMBL8621420 | 0.80 | UTS2R (0.45) | CNR1UTS2R | |
| SCHEMBL8200288 | 0.80 | RELA (0.36) | CNR1CNR2UTS2R | |
| SCHEMBL8792831 | 0.79 | SIGMAR1 (0.43) | UTS2R | |
| SCHEMBL8621717 | 0.79 | TPH1 (0.44) | PTGESTPH1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017956-A | AN ANTITUMOR AGENT, AN ENZYME INHIBITOR FOR INHIBITING PROTEIN-FARNESYL TRANSFERASE TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5919786-A | ANTITUMOR AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| US-5849747-A | N, n-disubstituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0805154-A1 | N,N-DISUBSTITUTED AMIC ACID DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |