Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937009 | 1.00 | TSHR (0.52) | TSHRCYP3A4TDP1ATMPRSS1 | |
| SCHEMBL22400566 | 1.00 | TSHR (0.52) | TSHRCYP3A4TDP1ATMPRSS1 | |
| SCHEMBL27536510 | 0.94 | TSHR (0.55) | TSHRCYP3A4TDP1ATMPRSS1 | |
| Methacrylic Acid SCHEMBL28292362 | 0.92 | TSHR (0.49) | TSHRCYP3A4TDP1ATMPRSS1 | |
| SCHEMBL16568414 | 0.87 | TSHR (0.41) | TSHRCYP3A4TDP1ATMPRSS1 | |
| SCHEMBL28283091 | 0.87 | TSHR (0.56) | TSHRCYP3A4TDP1ATMPRSS1 | |
| SCHEMBL8962379 | 0.86 | TSHR (0.48) | TSHRCYP3A4TDP1ATMPRSS1 | |
| Methacrylic Acid SCHEMBL27427055 | 0.86 | TSHR (0.45) | TSHRCYP3A4TDP1ATMPRSS1 | |
| SCHEMBL14660235 | 0.85 | TSHR (0.55) | TSHRCYP3A4TDP1ATMPRSS1 | |
| SCHEMBL4239989 | 0.83 | TSHR (0.59) | TSHRCYP3A4TDP1ATMPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704413-B1 | Ceramics sheet and production method for same | NIPPON CATALYTIC CHEM IND (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0202290-B1 | DISPERSANTS | INTERNATIONAL PAINT Public Limited Company (GB) | 1989-04-12 | — | — | EP | disclosed |