SCHEMBL8204958

SCHEMBL8204958

c1ccc(Cc2c(-c3ccccc3)cc3ccccn23)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
HTT P42858 4/20 0.47
THRB P10828 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
HRH3 Q9Y5N1 2/20 0.40
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
RECQL P46063 1/20 0.39
HPGD P15428 3/20 0.38
ALOX12 P18054 2/20 0.38
GAA P10253 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CHEK1 O14757 1/20 0.38
LIMK1 P53667 1/20 0.38
MAPK14 Q16539 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8205262 0.81 MAPT (0.57) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL27953291 0.75 MAPT (0.41) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL17478017 0.74 MAPT (0.49) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL21589060 0.73 MAPT (0.48) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL9187424 0.73 MAPT (0.59) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL7171515 0.72 MAPT (0.47) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL1435606 0.72 MAPT (0.57) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL16363728 0.72 MAPT (0.57) MAPTL3MBTL1NPC1RAB9AHTT
Iodide SCHEMBL10843424 0.72 MAPT (0.57) MAPTL3MBTL1NPC1RAB9AHTT
SCHEMBL10604301 0.71 MAPT (0.57) MAPTL3MBTL1NPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed