Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14205655 | 0.80 | CNR1 (0.54) | CNR1MAPTLMNARXRACNR2 | |
| SCHEMBL5058677 | 0.79 | CNR1 (0.66) | CNR1MAPTRXRACNR2TP53 | |
| SCHEMBL8213526 | 0.78 | CNR1 (0.39) | CNR1MAPTLMNATHRBTSHR | |
| SCHEMBL13807777 | 0.77 | CNR1 (0.51) | CNR1MAPTLMNARXRACNR2 | |
| SCHEMBL14206922 | 0.73 | CNR1 (0.46) | CNR1MAPTLMNACNR2CYP3A4 | |
| SCHEMBL14043678 | 0.70 | CNR1 (0.47) | CNR1MAPTLMNARXRACNR2 | |
| SCHEMBL13807944 | 0.70 | CNR1 (0.46) | CNR1MAPTRXRACNR2TP53 | |
| SCHEMBL8213532 | 0.69 | MAPT (0.39) | CNR1MAPTLMNACNR2TP53 | |
| SCHEMBL8212751 | 0.68 | POLB (0.45) | CNR1MAPTLMNARXRACNR2 | |
| SCHEMBL11883523 | 0.67 | CA1 (0.68) | MAPTLMNATHRBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048648-A2 | CB1-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-04-24 | — | — | WO | disclosed |