Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8205154

CCCCCC1CC(C)(C)NC(C)(C)C1.N

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.33
EPHX1 P07099 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
GBA1 P04062 3/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30
CYP19A1 P11511 3/20 0.30
SPHK1 Q9NYA1 1/20 0.30
GUSB P08236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15707671 0.96 ALDH1A1 (0.39) CYP1A2ALDH1A1TSHRGAAEPHX1
SCHEMBL16912864 0.96 ALDH1A1 (0.39) CYP1A2ALDH1A1TSHRGAAEPHX1
SCHEMBL12352241 0.96 ALDH1A1 (0.39) CYP1A2ALDH1A1TSHRGAAEPHX1
SCHEMBL9516918 0.96 ALDH1A1 (0.39) CYP1A2ALDH1A1TSHRGAAEPHX1
SCHEMBL16912862 0.96 ALDH1A1 (0.39) CYP1A2ALDH1A1TSHRGAAEPHX1
SCHEMBL15569964 0.96 ALDH1A1 (0.39) CYP1A2ALDH1A1TSHRGAAEPHX1
SCHEMBL15570217 0.96 ALDH1A1 (0.39) CYP1A2ALDH1A1TSHRGAAEPHX1
SCHEMBL4727634 0.91 CYP1A2 (0.43) CYP1A2ALDH1A1TSHRGAAMEN1
SCHEMBL818726 0.87 TSHR (0.36) TSHRGAA
SCHEMBL10621109 0.87 TSHR (0.36) TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062270-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 2000-12-27 EP claimed
WO-1999046323-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 1999-09-16 WO claimed
EP-1062270-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 2000-12-27 EP disclosed
WO-1999046323-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 1999-09-16 WO disclosed