Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | PLAT | P00750 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177312 | 0.85 | KDM4E (0.53) | GAAPLATKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL8186110 | 0.83 | ALDH1A1 (0.39) | GAAPLATKDM4EL3MBTL1ALPI | |
| SCHEMBL8191386 | 0.82 | PLAT (0.49) | GAAPLATKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9204181 | 0.78 | KDM4E (0.45) | GAAPLATKDM4EL3MBTL1ALPI | |
| SCHEMBL8190368 | 0.73 | KDM4E (0.51) | GAAPLATKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL16534821 | 0.73 | PLAT (0.39) | GAAPLATKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL16534541 | 0.73 | KDM4E (0.56) | GAAPLATKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL8188074 | 0.72 | KDM4E (0.50) | GAAPLATKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL8191989 | 0.72 | KDM4E (0.50) | GAAPLATKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL8176462 | 0.72 | KDM4E (0.49) | GAAPLATKDM4EL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021447-A1 | PYRROLOPYRAZOLOPYRIMIDINE COMPOUND AND MEDICINE COMPRISING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998033799-A1 | PYRROLOPYRAZOLOPYRIMIDINE COMPOUND AND MEDICINE COMPRISING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1998-08-06 | — | — | WO | disclosed |