SCHEMBL8205266

SCHEMBL8205266

O=C1c2ccccc2Cc2ccc3c(O)cccc3c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALOX15 P16050 2/20 0.53
TSHR P16473 2/20 0.53
HSD17B10 Q99714 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
USP2 O75604 1/20 0.53
HPN P05981 1/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX5 P09917 1/20 0.53
THRB P10828 1/20 0.53
PTGS1 P23219 1/20 0.53
PDE4A P27815 1/20 0.53
KDR P35968 1/20 0.53
SIRT5 Q9NXA8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
HRH3 Q9Y5N1 1/20 0.53
MAOA P21397 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703055 0.89 MAOA (0.59) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL7742221 0.84 MAOA (0.53) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL29549838 0.84 MAPT (0.75) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL1204733 0.84 MAPT (0.75) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL11481878 0.82 MAOA (0.50) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL11385694 0.79 MAOA (0.47) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL6418805 0.78 MAOA (0.57) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL23839 0.78 MAOA (0.57) ALDH1A1MAPTMEN1KMT2AMAOA
SCHEMBL769934 0.76 MAOA (0.71) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL11662031 0.76 MAOA (0.50) ALDH1A1MAPTMEN1KMT2AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992010555-A1 FLUORESCENT COMPOUNDS FOR ABSORPTION AND RE-EMISSION OF RADIATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO claimed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
WO-1992010555-A1 FLUORESCENT COMPOUNDS FOR ABSORPTION AND RE-EMISSION OF RADIATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
US-5095099-A Fluorescent compounds for absorption and re-emission of radiation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-10 US disclosed
US-4311565-A REDUCTION, CYCLIZATION CIBA-GEIGY AG (CH) 1982-01-19 US disclosed