Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.61 |
| ▸ | RXRB | P28702 | 2/20 | 0.61 |
| ▸ | RXRG | P48443 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622117 | 0.89 | RXRA (0.67) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL8622118 | 0.89 | RXRA (0.67) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL7089209 | 0.88 | RXRA (0.61) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL8622187 | 0.88 | RXRA (0.61) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL4427849 | 0.88 | RXRA (0.61) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL8622185 | 0.88 | RXRA (0.61) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL8619481 | 0.85 | RXRA (0.59) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL7221378 | 0.85 | RXRA (0.59) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL8205297 | 0.82 | HIF1A (0.50) | RXRARXRBRXRGMAPTL3MBTL1 | |
| SCHEMBL7779845 | 0.82 | HIF1A (0.50) | RXRARXRBRXRGMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114342-A | 2-(O-[pyrimidin-4-yl]methylenoxy)phenylacetic acid derivatives and their use for controlling harmful fungi and animal pests | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |