Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.66 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564585 | 0.93 | SLC1A3 (0.59) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL25413770 | 0.90 | HTT (0.68) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL2139878 | 0.87 | HTT (0.65) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL11317170 | 0.87 | HTT (0.65) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL2139876 | 0.87 | HTT (0.65) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL6605706 | 0.87 | HTT (0.68) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL18254066 | 0.86 | HTT (0.81) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL2677967 | 0.86 | SLC1A3 (0.70) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL16298087 | 0.86 | HTT (0.63) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL11507954 | 0.86 | HTT (0.63) | HTTSLC1A3SLC1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057419-A | DRUGS AND IMAGES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |