Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205371 | 0.93 | HTT (0.67) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL14985684 | 0.92 | SLC1A3 (0.69) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL22648528 | 0.85 | SLC1A3 (0.56) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL25413770 | 0.84 | HTT (0.68) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL1667805 | 0.83 | HTT (0.72) | HTTLMNASMN1; SMN2FOLH1TGM2 | |
| SCHEMBL16378068 | 0.83 | SLC1A3 (0.60) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL1734009 | 0.83 | CTSL (0.56) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL3319289 | 0.83 | CTSL (0.56) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL15697210 | 0.83 | HTT (0.63) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL8437001 | 0.83 | HTT (0.63) | SLC1A3SLC1A1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541497-A1 | Prolineamide derivatives as enhancers of learning processes and memory and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1993-05-12 | — | — | EP | disclosed |