Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.73 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832471 | 0.84 | NISCH (1.00) | NISCHMAOBADRA1DADRA1AADRA1B | |
| SCHEMBL9579892 | 0.82 | NISCH (0.81) | NISCH | |
| SCHEMBL8203361 | 0.79 | NISCH (0.75) | NISCHMAOBADRA1AMAOA | |
| Hydrochloric Acid SCHEMBL8198861 | 0.78 | NISCH (0.58) | NISCHMAOBADRA1AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL7736358 | 0.78 | NISCH (0.58) | NISCHMAOBADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7736143 | 0.77 | NISCH (0.57) | NISCHMAOBADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7736355 | 0.77 | NISCH (0.57) | NISCHMAOBADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7736140 | 0.77 | NISCH (0.57) | NISCHMAOBADRA1DADRA1AADRA1B | |
| SCHEMBL8200508 | 0.76 | NISCH (0.50) | NISCHMAOBADRA1DADRA1AADRA1B | |
| SCHEMBL8187776 | 0.75 | NISCH (0.55) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |