Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 0.75 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195752 | 0.89 | MAOB (0.69) | NISCHMAOAMAOB | |
| SCHEMBL8832471 | 0.86 | NISCH (1.00) | NISCHMAOAMAOBADRA1AALDH1A1 | |
| SCHEMBL5476725 | 0.80 | NISCH (0.79) | NISCHLMNARECQLTOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL8198861 | 0.79 | NISCH (0.58) | NISCHMAOAMAOBHTR1DADRA1A | |
| SCHEMBL8205384 | 0.79 | NISCH (0.73) | NISCHMAOAMAOBADRA1A | |
| SCHEMBL27662630 | 0.77 | ADRA2A (0.61) | NISCH | |
| SCHEMBL6823761 | 0.76 | NISCH (0.59) | NISCHMAOAMAOBRECQLTOP2A | |
| Hydrochloric Acid SCHEMBL7736152 | 0.75 | NISCH (0.57) | NISCHMAOAMAOBRECQLTOP2A | |
| SCHEMBL8141372 | 0.74 | NISCH (1.00) | NISCHMAOBLMNARECQLTOP2A | |
| Hydrochloric Acid SCHEMBL7736155 | 0.74 | NISCH (0.56) | NISCHMAOAMAOBTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |