Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199294 | 0.90 | GAA (0.35) | AXLKDM4EGAAHTTALDH1A1 | |
| SCHEMBL8271519 | 0.88 | SLC6A4 (0.37) | KDM4EGAAHTTALDH1A1 | |
| SCHEMBL8206449 | 0.82 | FNTA (0.45) | — | |
| SCHEMBL8207539 | 0.80 | PTGDR2 (0.35) | KDM4EGAAHTTALDH1A1 | |
| SCHEMBL7247059 | 0.79 | KDM4E (0.38) | AXLNR4A2KDM4EPOLQOPRK1 | |
| SCHEMBL7247057 | 0.79 | KDM4E (0.38) | AXLNR4A2KDM4EPOLQOPRK1 | |
| SCHEMBL8206760 | 0.79 | KDM4E (0.38) | KDM4EGAAHTTALDH1A1 | |
| SCHEMBL8210020 | 0.78 | KDM4E (0.32) | KDM4EGAAHTTALDH1A1 | |
| SCHEMBL8205725 | 0.78 | EIF4E (0.33) | GAA | |
| SCHEMBL8205766 | 0.76 | GAA (0.38) | AXLKDM4EGAAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |