SCHEMBL8205646

SCHEMBL8205646

Cc1ccc(I)cc1C1=NCCN1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 17/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8203143 0.98 NISCH (0.65) NISCH
SCHEMBL7853593 0.84 NISCH (0.51) NISCH
SCHEMBL11517317 0.80 NISCH (0.67) NISCH
SCHEMBL1626317 0.79 NISCH (1.00) NISCH
Hydrochloric Acid SCHEMBL8202289 0.76 NISCH (0.63) NISCH
SCHEMBL11516541 0.76 NISCH (0.66) NISCH
SCHEMBL9855792 0.75 NISCH (0.60) NISCH
SCHEMBL10112571 0.73 NISCH (0.60) NISCH
SCHEMBL11517310 0.73 NISCH (0.60) NISCH
SCHEMBL11739268 0.72 NISCH (0.84) NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000078726-A1 IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES ELI LILLY AND COMPANY (US) 2000-12-28 WO disclosed