Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255717 | 0.87 | TLR9 (0.38) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL24805444 | 0.79 | TLR9 (0.43) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL1629581 | 0.78 | TLR9 (0.48) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL5011366 | 0.78 | GAA (0.45) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL5412423 | 0.78 | CA12 (0.42) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL2342945 | 0.78 | GAA (0.52) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL5557903 | 0.78 | GAA (0.52) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL14779302 | 0.77 | TLR9 (0.47) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL4969119 | 0.77 | GAA (0.46) | TLR9GAAVDRCA1CA2 | |
| SCHEMBL14779220 | 0.77 | GAA (0.46) | TLR9GAAVDRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |