SCHEMBL8205686

SCHEMBL8205686

Cc1ccc(OC(=O)c2ccccc2O)c(C)c1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.55
HPGD P15428 3/20 0.55
KDM4E B2RXH2 3/20 0.55
ALDH1A1 P00352 3/20 0.55
ALOX15 P16050 1/20 0.51
KMT2A Q03164 4/20 0.51
ESR1 P03372 2/20 0.51
ESR2 Q92731 2/20 0.51
MEN1 O00255 2/20 0.51
LMNA P02545 3/20 0.50
TSHR P16473 3/20 0.50
RAB9A P51151 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.46
MAPT P10636 2/20 0.45
GAA P10253 2/20 0.45
HTT P42858 1/20 0.44
POLB P06746 1/20 0.44
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12919771 0.96 HSD17B10 (0.59) HSD17B10HPGDKDM4EALDH1A1ALOX15
SCHEMBL891120 0.83 HSD17B10 (0.67) HSD17B10HPGDKDM4EALDH1A1ALOX15
SCHEMBL2833936 0.83 MAPT (0.56) HPGDALDH1A1KMT2AESR1ESR2
SCHEMBL29042646 0.81 HSD17B10 (0.54) HSD17B10HPGDKDM4EALDH1A1ALOX15
SCHEMBL9421256 0.79 KMT2A (0.52) KMT2AMEN1L3MBTL1MAPT
SCHEMBL11771978 0.79 HSP90AA1 (0.45) HSD17B10HPGDKDM4EALDH1A1ALOX15
SCHEMBL2877383 0.78 KMT2A (0.54) KDM4EKMT2AESR1ESR2MEN1
SCHEMBL1603005 0.77 HSD17B10 (0.73) HSD17B10HPGDKDM4EALDH1A1ALOX15
SCHEMBL17614669 0.76 MAPT (0.54) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL9305775 0.76 THRA (0.45) HSD17B10HPGDKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US claimed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US disclosed