Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 9/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014716 | 0.88 | ELANE (0.47) | — | |
| SCHEMBL8520518 | 0.88 | ELANE (0.44) | — | |
| SCHEMBL8205698 | 0.86 | MEN1 (0.48) | MEN1KMT2AACELMNALTA4H | |
| SCHEMBL15765656 | 0.85 | PREP (0.42) | ACE2 | |
| SCHEMBL13014790 | 0.83 | PREP (0.41) | LMNAACE2 | |
| SCHEMBL13062430 | 0.82 | MAPT (0.41) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL6978337 | 0.77 | DPP4 (0.61) | ACERENKDM4EF2LMNA | |
| SCHEMBL17305538 | 0.77 | DPP4 (0.61) | ACERENKDM4EF2LMNA | |
| SCHEMBL30534327 | 0.77 | DPP4 (0.61) | ACERENKDM4EF2LMNA | |
| SCHEMBL20485168 | 0.76 | ACE (0.62) | MEN1KMT2AACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033389-A2 | MACROCYCLIC HCV INHIBITORS AND THEIR USES | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |