Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 7/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205696 | 0.86 | MEN1 (0.47) | MEN1KMT2AACELTA4HLMNA | |
| SCHEMBL4957308 | 0.79 | ACE (0.45) | MEN1KMT2AACELMNA | |
| SCHEMBL4957323 | 0.79 | ACE (0.45) | MEN1KMT2AACELMNA | |
| SCHEMBL20485168 | 0.77 | ACE (0.62) | MEN1KMT2AACE | |
| SCHEMBL18619558 | 0.77 | ACE (0.62) | MEN1KMT2AACE | |
| SCHEMBL8208603 | 0.76 | ELANE (0.56) | MEN1KMT2AACEELANE | |
| SCHEMBL10404382 | 0.75 | POLB (0.54) | MEN1KMT2AACEELANELTA4H | |
| SCHEMBL8520518 | 0.75 | ELANE (0.44) | ELANE | |
| SCHEMBL20484667 | 0.75 | ELANE (0.61) | MEN1KMT2AACEELANEITGB3 | |
| SCHEMBL13014716 | 0.75 | ELANE (0.47) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033389-A2 | MACROCYCLIC HCV INHIBITORS AND THEIR USES | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |