Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873213 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL182466 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL2789146 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL10703302 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL9354133 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL7044918 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL7044585 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL1354834 | 1.00 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL21679740 | 0.97 | LMNA (0.46) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL21679715 | 0.97 | LMNA (0.46) | LMNATSHRALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153322-A | Methods for making fluorinated surface modifying agents, methods of using same and products made using same | HOUSTON, UNIVERSITY OF | 2000-11-28 | — | — | US | disclosed |
| WO-1998040169-A1 | METHODS FOR MAKING FLUORINATED SURFACE MODIFYING AGENTS, METHODS OF USING SAME AND PRODUCTS MADE USING SAME | THE UNIVERSITY OF HOUSTON (US) | 1998-09-17 | — | — | WO | disclosed |