Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11497597 | 0.96 | ALDH1A1 (0.50) | TSHRALDH1A1 | |
| Propane SCHEMBL14841763 | 0.91 | TSHR (0.44) | TSHRALDH1A1MEN1LMNAKMT2A | |
| Propane SCHEMBL3395511 | 0.91 | TSHR (0.44) | TSHRALDH1A1MEN1LMNAKMT2A | |
| Alcohol SCHEMBL9416476 | 0.89 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| Butane SCHEMBL20394152 | 0.87 | ALDH1A1 (0.41) | TSHRALDH1A1MEN1LMNAKMT2A | |
| Butane SCHEMBL967967 | 0.87 | ALDH1A1 (0.41) | TSHRALDH1A1MEN1LMNAKMT2A | |
| Methyl Alcohol SCHEMBL28097701 | 0.86 | ALDH1A1 (0.47) | TSHRALDH1A1MEN1LMNAKMT2A | |
| Ethane SCHEMBL11686899 | 0.86 | ALDH1A1 (0.47) | TSHRALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL2508249 | 0.85 | ALDH1A1 (0.54) | TSHRALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL157380 | 0.85 | ALDH1A1 (0.54) | TSHRALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553156-B1 | REFRIGERATING MACHINE OIL AND WORKING FLUID COMPOSITION FOR REFRIGERATING MACHINES | JXTG NIPPON OIL & ENERGY CORP (JP) | 2023-11-08 | — | — | EP | claimed |
| EP-3609969-B1 | WATER BORNE DRY LAMINATION BONDING AGENT WITH HEAT RESISTANCE IMPROVEMENT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-11-01 | — | — | EP | claimed |
| EP-3281933-B1 | (METH)ACRYLATE MANUFACTURING METHOD | TOAGOSEI CO LTD (JP) | 2020-08-19 | — | — | EP | claimed |
| CN-110628007-A | Modified unsaturated polyester resin and synthesis process thereof | 永嘉县东大合成化工有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-110144172-A | A kind of EB solidification hot-fusible pressure-sensitive adhesive, preparation method and applications | 中广核达胜加速器技术有限公司 | 2019-08-20 | — | — | CN | claimed |
| CN-110101605-A | A kind of seven days lipsticks | 广州科恩生物技术有限公司 | 2019-08-09 | — | — | CN | claimed |
| EP-2610329-B1 | WORKING FLUID COMPOSITION FOR REFRIGERATING MACHINES | JXTG NIPPON OIL & ENERGY CORP (JP) | 2019-06-26 | — | — | EP | claimed |
| CN-106832205-B | A kind of shape memory modified polyurethane resin and preparation method thereof | 长兴材料工业（广东）有限公司 | 2019-06-18 | — | — | CN | claimed |
| EP-3133058-B1 | MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD | TOAGOSEI CO LTD (JP) | 2019-05-29 | — | — | EP | claimed |
| CN-109456566-A | A kind of high notch impact strength ABS material and preparation method thereof | 刘景典 | 2019-03-12 | — | — | CN | claimed |
| JP-2004505009-A | — | — | 2004-02-19 | — | — | JP | claimed |
| EP-1044168-B1 | POLYLACTATE RELEASE COMPOUNDS AND METHODS OF USING SAME | REGENESIS BIOREMEDIATION PRODU (US) | 2003-08-27 | — | — | EP | claimed |
| WO-2001052868-A9 | COMBINATIONS FOR TREATING NEOPLASMS | YU BAOFA (US) | 2003-01-16 | — | — | WO | claimed |
| WO-2002062867-A1 | SOLID EPOXIDIC CYCLOALIPHATIC HYDROXYLATE RESINS, PREPARATION PROCESS, AND COMPOSITIONS OF HARDENABLE POWDERBASE PAINTS CONTAINING THE SAID RESINS | SOLUTIA ITALY S.R.L. (IT) | 2002-08-15 | — | — | WO | claimed |
| US-20020044919-A1 | Combinations and methods for treating neoplasms | YU, BAOFA | 2002-04-18 | — | — | US | claimed |
| WO-2001052868-A1 | COMBINATIONS FOR TREATING NEOPLASMS | YU BAOFA (US) | 2001-07-26 | — | — | WO | claimed |
| EP-0455370-B2 | The incorporation of additives into polyesters | METACOL LIMITED (GB) | 2000-08-09 | — | — | EP | claimed |
| EP-0480479-B1 | Use of a lubricant for compressors using a hydrofluorocarbon refrigerant containing no chlorine | JAPAN ENERGY CORP (JP) | 1997-03-26 | — | — | EP | claimed |
| EP-0468729-B1 | Lubrication of vapour compression heat transfer systems | CASTROL LTD (GB) | 1996-01-10 | — | — | EP | claimed |
| EP-0269569-B1 | ESTERIFICATION PROCESS WITH CALCIUM HYDROXYBENZYL PHOSPHONATE-PHENOL SULFIDE CATALYST SYSTEM | CIBA-GEIGY AG (CH) | 1992-05-13 | — | — | EP | claimed |