SCHEMBL8205993

SCHEMBL8205993

CC(=O)N1[CH]NCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL603100 0.68
SCHEMBL20604912 0.64
SCHEMBL1208896 0.64
SCHEMBL1476813 0.61
SCHEMBL2479431 0.60
SCHEMBL5969104 0.60 NOTUM (0.32)
SCHEMBL310712 0.59
SCHEMBL1206985 0.59
SCHEMBL5433 0.57
SCHEMBL603099 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000032586-A1 METHOD FOR PREPARING 3-CHROMENE DERIVATIVES, USE OF SAID DERIVATIVES FOR PREPARING THIAZOLIDINONES RHODIA CHIMIE (FR) 2000-06-08 WO disclosed
US-4725600-A Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-02-16 US disclosed
EP-0168262-A2 Pyrimidine derivatives, processes for preparation thereof and use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-01-15 EP disclosed