Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BCL6 | P41182 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28151137 | 0.97 | BCL6 (0.47) | KMT2ABCL6HPGDSCHUKJAK1 | |
| SCHEMBL28151054 | 0.93 | BCL6 (0.50) | KMT2ABCL6JAK1TYK2CTSC | |
| SCHEMBL1934159 | 0.83 | KMT2A (0.69) | KMT2AHPGDSCTSCAXLLATS1 | |
| SCHEMBL1937546 | 0.81 | KMT2A (0.71) | KMT2AHPGDSCTSCAXLLATS1 | |
| SCHEMBL1976350 | 0.81 | LATS1 (0.56) | KMT2AAXLLATS1 | |
| SCHEMBL1977604 | 0.80 | HPGDS (0.43) | KMT2AHPGDSCHUKJAK1TYK2 | |
| SCHEMBL12556630 | 0.80 | JAK1 (0.59) | KMT2AHPGDSCHUKJAK1TYK2 | |
| SCHEMBL993784 | 0.79 | KMT2A (0.64) | KMT2AHPGDSCTSCAXLLATS1 | |
| SCHEMBL19174514 | 0.79 | KMT2A (0.68) | KMT2ABCL6HPGDSCHUKJAK1 | |
| SCHEMBL31403169 | 0.79 | JAK1 (0.57) | KMT2AHPGDSCHUKJAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341145-B | Chemical compound | 博拉公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114341145-A | Chemical compound | 博拉公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2008052934-A1 | NOVEL SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-05-08 | — | — | WO | disclosed |