Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421905 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7426573 | 0.82 | KDM4E (0.61) | TP53RECQLALDH2ALDH1A1MEN1 | |
| SCHEMBL8207916 | 0.80 | TAAR1 (0.78) | TAAR1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7889391 | 0.80 | KMT2A (0.68) | TP53ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14829398 | 0.79 | TAAR1 (0.76) | TAAR1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20915168 | 0.79 | MAPT (0.64) | TP53TAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL135251 | 0.79 | FLT3 (0.62) | RECQLALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8206811 | 0.79 | TAAR1 (0.62) | RECQLTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL8210444 | 0.79 | KMT2A (0.61) | TP53RECQLTAAR1ALDH1A1MEN1 | |
| Bicarbonate SCHEMBL7421513 | 0.78 | ALDH1A1 (0.56) | TP53CRHBPRECQLCRHR2ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |