Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 7/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 10/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81616 | 1.00 | GABRG2 (0.40) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL80873 | 0.94 | GABRG2 (0.40) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL81604 | 0.92 | PDK2 (0.41) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL81614 | 0.92 | PDK2 (0.41) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL82048 | 0.92 | PDK2 (0.41) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL12617737 | 0.91 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL81615 | 0.90 | PDK2 (0.39) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL80919 | 0.89 | PDK2 (0.42) | PDK2KMT2A | |
| SCHEMBL17324136 | 0.88 | PDK2 (0.40) | GABRG2GABRB3GABRA5GABRA3PDK2 | |
| SCHEMBL80361 | 0.88 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA3PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20120049176-A1 | AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120049176-A1 | AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-8110685-B2 | Efficient, durable electron transport layers; low driving voltage; simple, low cost production | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-8110685-B2 | Efficient, durable electron transport layers; low driving voltage; simple, low cost production | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20080154040-A1 | AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20080154040-A1 | AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154040-A1 | AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE | AZI2, CYP1A2, CYP2C19 | GABRG2 1582/4885GABRB3 1208/4885GABRA5 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.