Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206280 | 0.97 | TAAR1 (0.46) | EPHX1GRIN2BTAAR1KDM4EKMT2A | |
| SCHEMBL8206272 | 0.97 | TAAR1 (0.46) | EPHX1GRIN2BTAAR1KDM4EKMT2A | |
| SCHEMBL8209750 | 0.97 | TAAR1 (0.46) | EPHX1GRIN2BTAAR1KDM4EKMT2A | |
| SCHEMBL8205244 | 0.94 | TAAR1 (0.49) | EPHX1GRIN2BTAAR1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL8209834 | 0.92 | GRIN2B (0.46) | EPHX1GRIN2BTAAR1SIGMAR1GRIN1 | |
| SCHEMBL8206923 | 0.92 | TAAR1 (0.54) | EPHX1GRIN2BTAAR1KDM4EKMT2A | |
| SCHEMBL8199243 | 0.90 | GRIN2B (0.46) | EPHX1GRIN2BTAAR1SIGMAR1GRIN1 | |
| SCHEMBL8208770 | 0.88 | GRIN2B (0.47) | GRIN2BKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8199053 | 0.85 | TAAR1 (0.50) | EPHX1GRIN2BTAAR1KDM4EKMT2A | |
| SCHEMBL8199188 | 0.84 | GRIN2B (0.40) | GRIN2BTAAR1SIGMAR1GRIN1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |