Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205279 | 0.94 | GRIN2B (0.48) | GRIN2BGRIN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8209750 | 0.91 | TAAR1 (0.46) | GRIN2BGRIN1KMT2AKDM4EMEN1 | |
| SCHEMBL8206272 | 0.91 | TAAR1 (0.46) | GRIN2BGRIN1KMT2AKDM4EMEN1 | |
| SCHEMBL8206280 | 0.91 | TAAR1 (0.46) | GRIN2BGRIN1KMT2AKDM4EMEN1 | |
| SCHEMBL8205244 | 0.89 | TAAR1 (0.49) | GRIN2BGRIN1KMT2AKDM4EMEN1 | |
| SCHEMBL8206586 | 0.88 | EPHX1 (0.46) | GRIN2BGRIN1KMT2AKDM4EMEN1 | |
| SCHEMBL8206923 | 0.85 | TAAR1 (0.54) | GRIN2BKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8199243 | 0.85 | GRIN2B (0.46) | GRIN2BGRIN1 | |
| SCHEMBL8209728 | 0.84 | HRH1 (0.42) | GRIN2BGRIN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8205354 | 0.83 | MEN1 (0.43) | GRIN2BGRIN1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |