Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8206732

CCCC(C)(C)[Si](C)(C)OC1=Cc2ccccc2[C@@H]1[Hf+2][C@H]1C(O[Si](C)(C)C(C)(C)CCC)=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8212327 0.84 CYP19A1 (0.31) CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL8212304 0.82
SCHEMBL7198207 0.82
Hydrochloric Acid SCHEMBL8463367 0.81
SCHEMBL6907797 0.81
Hydrochloric Acid SCHEMBL7940339 0.81
Hydrochloric Acid SCHEMBL6906084 0.80
Hydrochloric Acid SCHEMBL6907578 0.79
Hydrochloric Acid SCHEMBL7936814 0.79
Hydrochloric Acid SCHEMBL7941413 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975644-A1 SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS, THEIR INTERMEDIATES AND METHODS FOR PREPARING THEM BOREALIS A/S (DK) 2000-02-02 EP disclosed
WO-1998046616-A1 SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS, THEIR INTERMEDIATES AND METHODS FOR PREPARING THEM BOREALIS A/S (DK) 1998-10-22 WO disclosed