⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080729 | 0.85 | — | — | |
| SCHEMBL19189815 | 0.83 | LMNA (0.43) | — | |
| SCHEMBL25976942 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL27383505 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL28133296 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL24216138 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL8862234 | 0.80 | LMNA (0.40) | — | |
| SCHEMBL442562 | 0.77 | — | — | |
| SCHEMBL19300404 | 0.77 | — | — | |
| SCHEMBL28340352 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693257-B | Gemcitabine derivative of benzenesulfonyl furazan modification and its production and use | 南通大学 | 2017-11-17 | — | — | CN | claimed |
| CN-113620863-B | Piperazine and piperidine derivatives, their synthesis and use | 内盖夫国家生物技术研究所 | 2024-04-05 | — | — | CN | disclosed |
| US-20230159511-A1 | TETRAHYDROISOQUINOLINE COMPOUNDS AS NRF2 ACTIVATORS | C4X DISCOVERY LIMITED (GB) | 2023-05-25 | — | — | US | disclosed |
| US-11560401-B2 | Method for preparing oligonucleic acid compound | NIPPON SHINYAKU CO., LTD. (JP) | 2023-01-24 | — | — | US | disclosed |
| US-20230018780-A1 | METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND | NIPPON SHINYAKU CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| US-20230014840-A1 | METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND | NIPPON SHINYAKU CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| EP-3187225-B1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2022-01-05 | — | — | EP | disclosed |
| CN-113620863-A | Novel piperazine and piperidine derivatives, their synthesis and their use | 内盖夫国家生物技术研究所 | 2021-11-09 | — | — | CN | disclosed |
| CN-113365627-A | VDAC inhibitors for the treatment of inflammatory bowel disease | 国家生物技术研究所公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-113347973-A | VDAC inhibitors for the treatment of autoimmune diseases | 国家生物技术研究所公司 | 2021-09-03 | — | — | CN | disclosed |
| EP-0180897-B1 | 5-FLUOROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0436902-A1 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0095764-B1 | 2-OXOAZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1987-09-02 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| EP-0053815-B1 | 2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-05-08 | — | — | EP | disclosed |
| EP-0021676-B1 | 3-METHOXY-2-OXOAZETIDINE DERIVATIVES AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1983-09-14 | — | — | EP | disclosed |