Ethylene

Ethylene

SCHEMBL820681

C=C.[Br-].[Zr+]C(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.32
CHRM1 known ✓ P11229 1/20 0.32
CHRM3 known ✓ P20309 1/20 0.32
HTR2A P28223 2/20 0.42
HTR6 P50406 1/20 0.34
KDM4E B2RXH2 2/20 0.32
CYP2D6 P10635 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL819410 0.96 HTR2A (0.38) HTR2AHTR6SIGMAR1
Hydrochloric Acid SCHEMBL8568820 0.92 HTR2A (0.41) HTR2AHTR6KDM4ECYP2D6LMNA
Ethylene SCHEMBL4337196 0.81 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6LMNA
SCHEMBL9056494 0.78 HTR2A (0.38) HTR2AHTR6KDM4ECYP2D6LMNA
Ethylene SCHEMBL4339097 0.77 HTR2A (0.34) HTR2AHTR6KDM4ECYP2D6LMNA
Ethylene SCHEMBL1535522 0.77 HTR2A (0.34) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL1535521 0.77 HTR2A (0.34) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL4337192 0.77 HTR2A (0.34) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL4339093 0.77 HTR2A (0.34) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL10454556 0.77 SIGMAR1 (0.38) HTR2AHTR6KDM4ECYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
EP-3480258-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2019-05-08 EP disclosed
US-20180355077-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2018-12-13 US disclosed
EP-2570437-B1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN TOSOH FINECHEM CORP (JP) 2018-07-04 EP disclosed
EP-2360191-B1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND PROCESS FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2017-03-29 EP disclosed
EP-2862889-B1 METHOD FOR PRODUCING SOLID POLYMETHYLALUMINOXANE COMPOSITION HAVING SMALL PARTICLE DIAMETER TOSOH FINECHEM CORP (JP) 2017-01-04 EP disclosed
US-9340630-B2 Method for manufacturing a small particle diameter product of solid polymethylaluminoxane composition TOSOH FINECHEM CORPORATION (JP) 2016-05-17 US disclosed
EP-2862889-A1 METHOD FOR PRODUCING SOLID POLYMETHYLALUMINOXANE COMPOSITION HAVING SMALL PARTICLE DIAMETER Tosoh Finechem Corporation (JP) 2015-04-22 EP disclosed
US-8975209-B2 Solid support-polymethylaluminoxane complex, method for producing same, olefin polymerization catalyst, and method for producing polyolefin TOSOH FINECHEM CORPORATION (JP) 2015-03-10 US disclosed
US-20150057418-A1 METHOD FOR MANUFACTURING A SMALL PARTICLE DIAMETER PRODUCT OF SOLID POLYMETHYLALUMINOXANE COMPOSITION TOSOH FINECHEM CORPORATION (JP) 2015-02-26 US disclosed
EP-1728795-B1 POLYMETHYLALUMINOXANE PRODUCT, PROCESS FOR PRODUCING THE SAME, POLYMERIZATION CATALYST, AND METHOD OF POLYMERIZING OLEFIN TOSOH FINECHEM CORP (JP) 2014-02-12 EP disclosed
US-8404880-B2 Solid polymethylaluminoxane composition and method for manufacturing same TOSOH FINECHEM CORPORATION (JP) 2013-03-26 US disclosed
EP-2570437-A1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN Tosoh Finechem Corporation (JP) 2013-03-20 EP disclosed
US-20130059990-A1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN TOSOH FINECHEM CORPORATION (JP) 2013-03-07 US disclosed
US-20110282017-A1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND METHOD FOR MANUFACTURING SAME TOSOH FINECHEM CORPORATION (JP) 2011-11-17 US disclosed
EP-2360191-A1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND PROCESS FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2011-08-24 EP disclosed
US-7910764-B2 Polymethylaluminoxane preparation, method of producing the same, polymerization catalyst, and polymerization method of olefins TOSOH FINECHEM CORPORATION (JP) 2011-03-22 US disclosed
US-20070197745-A1 Polymethylaluminoxane preparation, method of producing the same, polymerization catalyst, and polymerization method of olefins TOSOH FINECHEM CORPORATION (JP) 2007-08-23 US disclosed
EP-1728795-A1 POLYMETHYLALUMINOXANE PRODUCT, PROCESS FOR PRODUCING THE SAME, POLYMERIZATION CATALYST, AND METHOD OF POLYMERIZING OLEFIN Tosoh Finechem Corporation (JP) 2006-12-06 EP disclosed