SCHEMBL8206945

SCHEMBL8206945

C=COC(=O)OCC(C)COC(=O)OC=CC

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29008011 0.80 MAPT (0.41) TSHR
SCHEMBL285034 0.77 TSHR (0.57) TSHR
SCHEMBL320955 0.70 TSHR (0.33) TSHR
SCHEMBL575321 0.70 TSHR (0.33) TSHR
SCHEMBL1092983 0.69
SCHEMBL284457 0.68 TSHR (0.32) TSHR
SCHEMBL13469505 0.68 TSHR (0.34) TSHR
SCHEMBL151311 0.67 GSTP1 (0.32)
SCHEMBL698511 0.67 MAPT (0.42) TSHR
SCHEMBL5794804 0.66 TSHR (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6166236-A Vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 2000-12-26 US disclosed
US-5070215-A Gas permeable contact lenses BAUSCH & LOMB INCORPORATED (US) 1991-12-03 US disclosed