SCHEMBL284457

SCHEMBL284457

C=COC(=O)OCC(COC(=O)OC=C)OC(=O)OC=C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SERPINE1 P05121 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13855388 0.81 TDP1 (0.35) TSHRALDH1A1LMNA
SCHEMBL3762376 0.81
SCHEMBL320955 0.77 TSHR (0.33) TSHR
SCHEMBL285034 0.77 TSHR (0.57) TSHRALDH1A1LMNA
SCHEMBL575321 0.77 TSHR (0.33) TSHR
SCHEMBL3759142 0.75
SCHEMBL10759977 0.73 CYP3A4 (0.36) TSHRSERPINE1ALDH1A1LMNA
SCHEMBL19712640 0.73
SCHEMBL14827538 0.72 TSHR (0.32) TSHRALDH1A1
SCHEMBL284797 0.72 TSHR (0.42) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898585-A1 PREPARATION OF A COMPOSITION COMPRISING AN ORGANIC PEROXIDE BY SOLVENT TRANSFER ARKEMA FRANCE (FR) 2021-10-27 EP claimed
WO-2020128337-A1 PREPARATION OF A COMPOSITION COMPRISING AN ORGANIC PEROXIDE BY SOLVENT TRANSFER ARKEMA FRANCE (FR) 2020-06-25 WO claimed
EP-3091050-B1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE SYNTHES GMBH (CH) 2018-07-18 EP claimed
US-9814801-B2 Thiol-ene polymerization with vinylesters and vinylcarbonate DePuy Synthes Products, Inc. (US) 2017-11-14 US claimed
EP-3091050-A1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE Synthes GmbH (CH) 2016-11-09 EP claimed
US-20160243279-A1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE SYNTHES GMBH (CH) 2016-08-25 US claimed
EP-2764049-B1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE SYNTHES GMBH (CH) 2016-08-17 EP claimed
EP-2764049-A1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE Synthes GmbH (CH) 2014-08-13 EP claimed
WO-2013052328-A1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE SYNTHES USA, LLC (US) 2013-04-11 WO claimed
US-20130084543-A1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE TECHNISCHE UNIVERSITAT WIEN (AT) 2013-04-04 US claimed
US-6166236-A Vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 2000-12-26 US claimed
EP-3898585-A1 PREPARATION OF A COMPOSITION COMPRISING AN ORGANIC PEROXIDE BY SOLVENT TRANSFER ARKEMA FRANCE (FR) 2021-10-27 EP disclosed
WO-2020128337-A1 PREPARATION OF A COMPOSITION COMPRISING AN ORGANIC PEROXIDE BY SOLVENT TRANSFER ARKEMA FRANCE (FR) 2020-06-25 WO disclosed
EP-3091050-B1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE SYNTHES GMBH (CH) 2018-07-18 EP disclosed
US-9814801-B2 Thiol-ene polymerization with vinylesters and vinylcarbonate DePuy Synthes Products, Inc. (US) 2017-11-14 US disclosed
EP-0396364-B1 Copolymers of vinyl carbonate and vinyl carbamate as contact lens material BAUSCH & LOMB (US) 1997-06-11 EP disclosed
US-5610252-A Vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1997-03-11 US disclosed
EP-0757033-A2 Vinyl carbonate and vinyl carbamate monomers for a contact lens material BAUSCH & LOMB INCORPORATED (US) 1997-02-05 EP disclosed
US-5070215-A Gas permeable contact lenses BAUSCH & LOMB INCORPORATED (US) 1991-12-03 US disclosed
EP-0396364-A2 Novel vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1990-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130084543-A1 THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE TMT1A, MGMT, CBS TSHR 2137/4885SERPINE1 4630/4885ALDH1A1 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.