Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 12/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207357 | 1.00 | OPRD1 (0.73) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8206416 | 0.98 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8206414 | 0.98 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8200451 | 0.97 | OPRD1 (0.71) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6863247 | 0.97 | OPRD1 (0.71) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6863243 | 0.97 | OPRD1 (0.71) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8200458 | 0.97 | OPRD1 (0.71) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6859160 | 0.93 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6859164 | 0.93 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8200039 | 0.93 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150524-A | MORPHINAN DERIVATIVES | CENES LTD. (GB) | 2000-11-21 | — | — | US | disclosed |
| EP-0960111-A1 | MORPHINE DERIVATIVES WITH ANALGESIC ACTIVITY | NYCOMED IMAGING AS (NO) | 1999-12-01 | — | — | EP | disclosed |
| WO-1997022606-A1 | MORPHINE DERIVATIVES WITH ANALGESIC ACTIVITY | NYCOMED IMAGING AS (NO) | 1997-06-26 | — | — | WO | disclosed |