Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283386 | 0.79 | DRD2 (0.31) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6852848 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6851965 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6851961 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6852852 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6860126 | 0.76 | KDM4E (0.30) | MAPTKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL6858680 | 0.76 | KDM4E (0.30) | MAPTKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL6860123 | 0.76 | KDM4E (0.30) | MAPTKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL6858678 | 0.76 | KDM4E (0.30) | MAPTKDM4ETSHR | |
| SCHEMBL11787789 | 0.74 | DRD2 (0.47) | DRD2DRD4MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021454-A1 | 2-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998006728-A1 | 2-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |