Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207605 | 0.91 | PPM1B (0.40) | ALDH1A1SMN1; SMN2LMNAPOLBATM | |
| SCHEMBL7669796 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAPOLBATM | |
| SCHEMBL7669797 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAPOLBATM | |
| SCHEMBL8213451 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAPOLBATM | |
| SCHEMBL1298046 | 0.77 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLBATM | |
| SCHEMBL2251674 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAPOLBATM | |
| SCHEMBL234282 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ATMCHRM2CHRM4CHRM5 | |
| SCHEMBL813586 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ATMCHRM2CHRM4CHRM5 | |
| SCHEMBL2583177 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ATMCHRM2CHRM4CHRM5 | |
| SCHEMBL812938 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ATMCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988299-A1 | POLYMERISABLE, OPTICALLY ACTIVE DIOXOLANE DIESTERS | Rolic AG (CH) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998055473-A1 | POLYMERISABLE, OPTICALLY ACTIVE DIOXOLANE DIESTERS | ROLIC AG (CH) | 1998-12-10 | — | — | WO | disclosed |