Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MGAM | O43451 | 6/20 | 0.67 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.67 |
| ▸ | FLT3 | P36888 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420010 | 0.93 | KDM4E (0.67) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8199918 | 0.92 | MGAM (0.64) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8211459 | 0.87 | MGAM (0.77) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8213046 | 0.86 | MGAM (0.73) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8207640 | 0.85 | KDM4E (0.65) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL7425023 | 0.85 | KDM4E (0.60) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8212882 | 0.83 | MGAM (0.64) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8207571 | 0.82 | CNR2 (0.58) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8210444 | 0.81 | KMT2A (0.61) | MAPTLMNAKDM4EALDH1A1HPGD | |
| Bicarbonate SCHEMBL7430289 | 0.81 | CNR2 (0.62) | MAPTLMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |