Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MGAM | O43451 | 6/20 | 0.64 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.64 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889391 | 0.90 | KMT2A (0.68) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL8207966 | 0.85 | MAPT (0.74) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL8211459 | 0.84 | MGAM (0.77) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL8213046 | 0.83 | MGAM (0.73) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL8206341 | 0.83 | CNR2 (0.55) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL8199918 | 0.82 | MGAM (0.64) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL8208112 | 0.81 | MEN1 (0.61) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL8212882 | 0.81 | MGAM (0.64) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL7426573 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL8210395 | 0.80 | TDP1 (0.58) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |