SCHEMBL82080

SCHEMBL82080

CNC(=O)c1cccc(C)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.71
HDAC6 Q9UBN7 2/20 0.71
SMN1; SMN2 Q16637 2/20 0.67
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
KCNK3 O14649 2/20 0.65
KCNK9 Q9NPC2 2/20 0.65
KCNH2 Q12809 1/20 0.65
RXFP1 Q9HBX9 1/20 0.59
POLB P06746 2/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
TP53 P04637 1/20 0.59
PARP1 P09874 1/20 0.59
MAPT P10636 1/20 0.57
CTDSP1 Q9GZU7 1/20 0.57
NT5E P21589 1/20 0.57
GRM5 P41594 1/20 0.56
TAS1R3 Q7RTX0 1/20 0.56
TAS1R1 Q7RTX1 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31540297 1.00 HDAC8 (0.71) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL5909363 0.87 HDAC8 (0.83) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL27668893 0.86 SMN1; SMN2 (0.70) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL28744940 0.86 HDAC8 (0.69) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL24931248 0.85 SMN1; SMN2 (0.89) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL12200279 0.84 MEN1 (0.87) SMN1; SMN2MEN1KMT2AKCNK3KCNK9
SCHEMBL21653856 0.84 SMN1; SMN2 (0.79) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL30929655 0.83 HDAC6 (1.00) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL5242529 0.83 HDAC6 (1.00) HDAC8HDAC6SMN1; SMN2MEN1KMT2A
SCHEMBL15328144 0.82 HDAC8 (0.65) HDAC8HDAC6SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 828 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118696036-A PARP1 inhibitors 突触活化疗法股份有限公司 2024-09-24 CN claimed
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US claimed
US-11066749-B2 Corrosion inhibition of HCL treatment fluids with environmentally compatible solvent HALLIBURTON ENERGY SERVICES, INC. (US) 2021-07-20 US claimed
US-20200173034-A1 Corrosion Inhibition of HCL Treatment Fluids with Environmentally Compatible Solvent HALLIBURTON ENERGY SERVICES, INC. (US) 2020-06-04 US claimed
US-10604850-B2 Corrosion inhibition of HCL treatment fluids with environmentally compatible solvent HALLIBURTON ENERGY SERVICES, INC. (US) 2020-03-31 US claimed
US-20180127882-A1 Corrosion Inhibition of HCL Treatment Fluids with Environmentally Compatible Solvent HALLIBURTON ENERGY SERVICES, INC. (US) 2018-05-10 US claimed
US-20170253582-A1 TRIAZOLE MODIFIED COUMARIN AND BIPHENYL AMIDE-BASED HSP90 INHIBITORS REATA PHARMACEUTICALS, INC. 2017-09-07 US claimed
EP-3154964-A1 TRIAZOLE MODIFIED COUMARIN AND BIPHENYL AMIDE-BASED HSP90 INHIBITORS The University of Kansas (US) 2017-04-19 EP claimed
WO-2016190865-A1 CORROSION INHIBITION OF HCL TREATMENT FLUIDS WITH ENVIRONMENTALLY COMPATIBLE SOLVENT HALLIBURTON ENERGY SERVICES, INC. (US) 2016-12-01 WO claimed
WO-2015192099-A1 TRIAZOLE MODIFIED COUMARIN AND BIPHENYL AMIDE-BASED HSP90 INHIBITORS THE UNIVERSITY OF KANSAS (US) 2015-12-17 WO claimed
EP-2646600-A1 CORROSION INHIBITOR COMPOSITIONS COMPRISING REACTION PRODUCTS OF ALDEHYDES AND AMIDES AND RELATED METHODS Halliburton Energy Services, Inc. (US) 2013-10-09 EP claimed
US-8361937-B2 Corrosion inhibitor compositions comprising reaction products of aldehydes and amides and related methods HALLIBURTON ENERGY SERVICES, INC. (US) 2013-01-29 US claimed
WO-2012072986-A1 CORROSION INHIBITOR COMPOSITIONS COMPRISING REACTION PRODUCTS OF ALDEHYDES AND AMIDES AND RELATED METHODS HALLIBURTON ENERGY SERVICES, INC. (US) 2012-06-07 WO claimed
US-20120142563-A1 Corrosion Inhibitor Compositions Comprising Reaction Products of Aldehydes and Amides and Related Methods HALLIBURTON ENERGY SERVICES, INC. (US) 2012-06-07 US claimed
US-12590070-B2 Adamantane derivatives as inhibitors of focal adhesion kinase SAMJIN PHARMACEUTICAL CO., LTD. (KR) 2026-03-31 US disclosed
EP-4644390-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF Beyang Therapeutics Co., Ltd. (CN) 2025-11-05 EP disclosed
EP-4074697-B1 NOVEL ADAMANTANE DERIVATIVES AS INHIBITORS OF FOCAL ADHESION KINASE SAMJIN PHARM CO LTD (KR) 2025-05-21 EP disclosed
US-4100192-A Inter-phenylene-PG amides THE UPJOHN COMPANY (US) 1978-07-11 US disclosed
US-4097489-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-06-27 US disclosed
US-3959269-A TRANQUILIZERS, SEDATIVES SANDOZ, INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor MAP3K20, MAP3K15, MAP3K1 HDAC8 677/4885HDAC6 581/4885SMN1; SMN2 2457/4885
US-20170253582-A1 TRIAZOLE MODIFIED COUMARIN AND BIPHENYL AMIDE-BASED HSP90 INHIBITORS HSP90AB1, HSP90AB2P, HSP90AA1 HDAC8 131/4885HDAC6 27/4885SMN1; SMN2 4736/4885
US-12590070-B2 Adamantane derivatives as inhibitors of focal adhesion kinase PTK2, CTTN, ADGRF1 HDAC8 2084/4885HDAC6 1678/4885SMN1; SMN2 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.