Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242529 | 1.00 | HDAC6 (1.00) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5389532 | 0.87 | HDAC8 (0.75) | HDAC6HDAC8MEN1KMT2AKCNK3 | |
| SCHEMBL9544991 | 0.86 | SMN1; SMN2 (0.76) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24931248 | 0.85 | SMN1; SMN2 (0.89) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11791484 | 0.84 | HDAC8 (0.79) | HDAC6HDAC8KDM4EEGLN2HDAC1 | |
| SCHEMBL82080 | 0.83 | HDAC8 (0.71) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31540297 | 0.83 | HDAC8 (0.71) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27819772 | 0.83 | HDAC8 (0.69) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2409358 | 0.82 | HDAC8 (0.67) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL315826 | 0.82 | HDAC8 (0.69) | HDAC6HDAC8SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084819-A | Thiazole derivative and application thereof in treatment of leukemia | 华东师范大学 | 2024-05-28 | — | — | CN | disclosed |