Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021888 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL1023293 | 0.80 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL1021870 | 0.77 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL1021872 | 0.77 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL7809824 | 0.76 | SLC6A3 (0.60) | SLC6A2SLC6A4SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL1023143 | 0.76 | SLC6A4 (0.60) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL6489924 | 0.76 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL5829675 | 0.75 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL2890215 | 0.75 | SLC6A4 (0.59) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL2890213 | 0.75 | SLC6A4 (0.59) | SLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971918-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998046600-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-10-22 | — | — | WO | disclosed |