Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.54 |
| ▸ | CA6 | P23280 | 6/20 | 0.54 |
| ▸ | CA7 | P43166 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 6/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA5A | P35218 | 4/20 | 0.54 |
| ▸ | CA4 | P22748 | 4/20 | 0.54 |
| ▸ | CA3 | P07451 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672610 | 0.78 | MEN1 (0.48) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8207235 | 0.77 | CA12 (0.64) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8210799 | 0.76 | CA12 (0.54) | CA12CA6CA7CA9CA14 | |
| SCHEMBL11507962 | 0.73 | CA12 (0.76) | CA12CA6CA7CA9CA14 | |
| SCHEMBL11337551 | 0.73 | ALDH1A1 (0.72) | CA12CA6CA7CA9CA14 | |
| SCHEMBL2808135 | 0.71 | MAOB (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL26603107 | 0.71 | KDM4E (0.69) | CA12CA6CA7CA9CA14 | |
| SCHEMBL978456 | 0.71 | KDM4E (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL29963204 | 0.71 | KDM4E (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8209478 | 0.70 | CA12 (0.61) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988298-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998055472-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | disclosed |