Iodide

Iodide

SCHEMBL8208149

CCCN1CCOCC1.I

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 1/20 0.48
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KEAP1 Q14145 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPK1 P28482 2/20 0.48
SIGMAR1 Q99720 2/20 0.48
CYP1A2 P05177 1/20 0.48
CHRM2 P08172 1/20 0.48
HTR2A P28223 1/20 0.48
SCN1A P35498 1/20 0.48
HTR2B P41595 1/20 0.48
KCNH2 Q12809 1/20 0.48
SCN2A Q99250 1/20 0.48
SCN3A Q9NY46 1/20 0.48
HRH3 Q9Y5N1 1/20 0.48
USP2 O75604 2/20 0.47
LMNA P02545 1/20 0.47
GLA P06280 1/20 0.45
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33271 0.97
Hydrogen Sulfide SCHEMBL28301039 0.95 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
Bromide SCHEMBL2812026 0.95 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
Water SCHEMBL28087307 0.95 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
SCHEMBL19478722 0.95 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
SCHEMBL31474386 0.95 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
Ammonia Solution, Strong SCHEMBL388879 0.95 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
SCHEMBL12386148 0.95 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
Hydrochloric Acid SCHEMBL8005745 0.95 MAPK1 (0.52) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1
SCHEMBL14849245 0.95 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KEAP1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6024807-A DEPOSITING METALLIC PLATINUM ONTO AN ELECTRICALLY CONDUCTIVE SUBSTRATE ECOLE POLUTECHNIQUE FEDERALE DE LAUSANNE (CH) 2000-02-15 US disclosed
EP-0852804-B1 PROCESS FOR MANUFACTURING AN ELECTRODE FOR AN ELECTROCHEMICAL DEVICE ECOLE POLYTECH (CH) 1999-10-27 EP disclosed
EP-0852804-A1 PROCESS FOR MANUFACTURING AN ELECTRODE FOR AN ELECTROCHEMICAL DEVICE ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) 1998-07-15 EP disclosed
WO-1997012382-A1 PROCESS FOR MANUFACTURING AN ELECTRODE FOR AN ELECTROCHEMICAL DEVICE ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) 1997-04-03 WO disclosed