Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820831 | 1.00 | ALDH1A1 (0.40) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL821066 | 0.90 | ALDH1A1 (0.38) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL821065 | 0.90 | ALDH1A1 (0.38) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL821362 | 0.90 | ALDH1A1 (0.39) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL821363 | 0.90 | ALDH1A1 (0.39) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL821296 | 0.88 | MAPT (0.40) | ALDH1A1NPSR1RECQLMAPTKMT2A | |
| SCHEMBL821295 | 0.88 | MAPT (0.40) | ALDH1A1NPSR1RECQLMAPTKMT2A | |
| SCHEMBL821379 | 0.87 | MAPT (0.37) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL821378 | 0.87 | MAPT (0.37) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL821127 | 0.87 | MAPT (0.43) | ALDH1A1RECQLMAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | claimed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | claimed |
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | disclosed |