Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | CCNH | P51946 | 2/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287655 | 0.86 | HTR1D (0.42) | HTR1DHTR1BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL774111 | 0.86 | SLC6A4 (0.43) | MAPTSLC6A4SLC6A2SLC6A3IDO1 | |
| SCHEMBL774639 | 0.86 | SLC6A4 (0.43) | MAPTSLC6A4SLC6A2SLC6A3IDO1 | |
| SCHEMBL8209129 | 0.86 | SLC6A4 (0.43) | HTR1BSLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL8507358 | 0.86 | HTR1D (0.45) | HTR1DHTR1BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1697454 | 0.86 | SLC6A4 (0.43) | MAPTSLC6A4SLC6A2SLC6A3IDO1 | |
| SCHEMBL9287650 | 0.86 | HTR1D (0.42) | HTR1DHTR1BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8209090 | 0.86 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL8506282 | 0.84 | HTR1D (0.44) | HTR1DHTR1BTP53MAPTSLC6A4 | |
| SCHEMBL8507170 | 0.84 | HTR1D (0.43) | HTR1DHTR1BSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998462-A | SEROTONIN RECEPTOR ANTAGONIST | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1999-12-07 | — | — | US | claimed |
| US-6100291-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-08-08 | — | — | US | disclosed |
| US-5998462-A | SEROTONIN RECEPTOR ANTAGONIST | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1999-12-07 | — | — | US | disclosed |